Tapering of prednisone should be done slowly using 1 mg decrements every couple weeks to a month. One should not deem it a failure to hold the patient on the lowest effective dose of prednisone. One should not deem it a failure to hold the patient on the lowest effective dose of prednisone. Detailed Prednisone dosage information for adults and children. Includes dosages for Osteoarthritis, Asthma - Maintenance, Rheumatoid Arthritis and more; plus renal, liver and dialysis adjustments. 5mg Prednisone Maintenance Dose Christmas discounts! Very cheap pills online, Secure and Anonymous. Licensed and Generic products for sale. Happy New Year!. Low Prices! 2018 For example, prednisone is used as a maintenance therapy drug for Addison's Disease where adults might be required to ingest a very small amount of prednisone 5mg in the morning as well as in the evening before bed. This dosage also works well in the treatment of congenital adrenal hyperplasia. Azathiprine supposedly can be used long term, but prednisone is most definitely NOT a long term or maintenance drug and can cause a wide variety of problems: according to the drug information, long-term side-effects include Cushing's syndrome, weight gain, osteoporosis, glaucoma, type II diabetes mellitus, and depression upon withdrawal. Of course if low dose prednisone doesn't do the trick for you then this would not matter but I believe it just might work in me. So far I haven't had the guts to try it. So far I haven't had the guts to try it. Detailed Prednisolone dosage information for adults and children. Includes dosages for Osteoarthritis, Asthma - Maintenance, Rheumatoid Arthritis and more; plus renal, liver and dialysis adjustments. I am now stable for one year while taking a maintenance dose of 5 mg prednisone and 3000 mg cellcept. After another year of stability the plan is to very slowly taper the cellcept to 2000 or 1500 mg cellcept. Is there any reason to taper the 5 mg prednisone to zero – or should it be maintained as “insurance”. Hi, andymb, I have been on a maintenance dose of 5mg for years now, increasing when I have an exacerbation. I have the usual side effects of the round face and tum, and have to take alendronic acid and ad cal tablets to protect my bones. You should carry the steroid warning card with you. Other corticoids, including methylprednisolone, hydrocortisone, prednisone, and prednisolone, are considered to be short acting (producing adrenocortical suppression for 11/4 to 1½ days following a single dose) and thus are recommended for alternate day therapy.